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The number of research reactors producing Mo99 is on the decline, whereas the demand for the Mo99 is
increasing. Many of these reactors are reaching their end of life, and replacement reactors are not being built.

Some of the leading processors’ are listed below

Maximum
Average no Share of Importance
capacity
Processor Country of Mo-99 per week annual Type of of Mo-99
Name production (6-day Ci total world Organisation 1 processing to the
weeks/year capacity organisation 2
99Mo)
ANM Australia 43 3 500 18% Governmental Very High
CNEA Argentina 46 400 2% Governmental High
Curium Netherlands 52 5 000 32% Commercial High
Semi-governmental/
IRE Belgium 52 3 500 22% High
commercial
United
NorthStar 52 750 5% Commercial High
States
NTP South Africa 44 3 000 16% Semi-governmental Very High
Rosatom
Russian
(RIAR and Federation 50 890 5% Semi-governmental Low
KARPOV)

Source: https://www.oecd-ilibrary.org/sites/67dec9af-en/index.html?itemId=/content/component/67dec9af-en#wrapper

Both the reactors and processing involve a lot of engineering automation and careful handling of the highly
radioactive elements. According to Transparency Market Research report titled, “Technetium-99m Market”, the
global Technetium-99m market was valued at US$ 2.7 Bn in 2019 and is projected to expand at a CAGR of 3.5%
from 2020 to 2030. Radio-pharma players drive the growth of Technetium-99m market; clinical trials applications;
ageing population increase; new drugs Testing; and an indication of disease mortality.

The stoppage of reactors or processing plants can impact the Molybdenum supply. Processing facilities need to be
located close to the reactor to avoid delay in transit. So integrated Reactor Processors are essential to a successful
Supply chain. Global Technetium-99m market includes GE Healthcare, Curium, Lantheus Medical Imaging, Inc.,
Mallinckrodt, Siemens Healthineers, Advanced Accelerator Applications, Bayer AG, Eckert & Ziegler, Advanced
Cyclotron Systems, Inc., Sumitomo Heavy Industries, Ltd., Philips, and Jubilant Life Sciences Limited.

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